Visual Atlas / Mycology

Chromoblastomycosis Agents: Sporulation Types

Original bench-card visual comparing how three chromoblastomycosis agents sporulate: Phialophora collarette phialides, Fonsecaea mixed denticulate types, and Cladophialophora long fragile chains.

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Bench card visual

Chromoblastomycosis agents: collarette, mixed denticulate, and long chains

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These agents share sclerotic bodies in tissue but differ in culture sporulation. Phialophora makes collarette phialides, Fonsecaea shows mixed denticulate sporulation, and Cladophialophora forms long fragile conidial chains.

PhialophoraCollarette phialides

Flask or cup-shaped phialides with a distinct saucer-like collarette. Oval conidia are produced through the apical pore and cluster near the opening.

FonsecaeaMixed denticulate sporulation

Mixed sporulation: single-celled conidia arise on short denticles around the conidiophore, with truncated short chains and some collarette types also present.

CladophialophoraLong fragile conidial chains

Long, sparsely branched, fragile chains of elliptical conidia without prominent shield cells. Chains break apart easily during mount preparation.

What to look for

Chromoblastomycosis sporulation anchors

Visual clueMeaningStudent shorthand
Collarette phialidesPhialophora typeSaucer-like collarette with conidia at the apical pore
Denticulate mixed sporulationFonsecaea typeConidia on short denticles around the conidiophore
Long fragile conidial chainsCladophialophora typeSparsely branched chains, no prominent shield cells
Sclerotic bodies in tissueShared tissue formAll three produce muriform sclerotic bodies in tissue
Interpretation table

Chromoblastomycosis agent interpretation guide

PatternWhat to call itHow to think about it
Collarette phialides with conidial clustersPhialophora-compatible morphologyConfirm by validated mold ID workflow
Mixed denticulate sporulationFonsecaea-compatible morphologyConfirm by validated mold ID workflow
Long fragile conidial chainsCladophialophora-compatible morphologyConfirm by validated mold ID workflow
Key takeaways
  • The agents share sclerotic bodies in tissue but differ in culture sporulation.
  • Collarette, denticulate, and long-chain patterns separate the three genera.
  • Mixed sporulation is a useful clue toward Fonsecaea.
Remember

Phialophora collarette, Fonsecaea denticulate mix, Cladophialophora long chains; all = sclerotic bodies in tissue.